Adanya korelasi kadar TNF-α antara pemeriksaan hapusan lesi dengan pemeriksaan darah perifer pasien stomatitis aftosa rekuren Correlation of TNF-α between lesional swab and peripheral blood of mononuclear cell of recurrent aphthous stomatitis patient

Authors

Ali Yusran, Bagian Oral Medicine, Fakultas Kedokteran Gigi Universitas Hasanuddin Makassar, IndonesiaFollow
Erni Marlina, Bagian Oral Medicine, Fakultas Kedokteran Gigi Universitas Hasanuddin Makassar, IndonesiaFollow
Sumintarti Sumintarti, Bagian Oral Medicine, Fakultas Kedokteran Gigi Universitas Hasanuddin Makassar, IndonesiaFollow

Abstract

Recurrent aphthous stomatitis (RAS)is a common oral mucosal disease in human. This disease affect 20-25% of
population. The etiology remains unclear, but some of cytokine such as TNF-α is suspected to contribute in the
pathogenesis of RAS. TNF-α is commonly measured by PBMC and lesional biopsy. These are invasive method and
high skilled requirement. Another study used lesional swab to measure this cytokine without correlating the result
with TNF-α measured by PBMC level. This study aimed to asses TNF-α level correlation between lesional swab and
PBM of RAS patients. The study involved 10 subjects by inclusion criteria. Subjects have lesion swab and PBMC
examined. Samples were analyzed by ELISA method. There is a correlation between lesional swab and PBMC of
TNF-α level RAS patients but this correlation did not statistically significant.

Recommended Citation

Yusran, Ali; Marlina, Erni; and Sumintarti, Sumintarti (2011) "Adanya korelasi kadar TNF-α antara pemeriksaan hapusan lesi dengan pemeriksaan darah perifer pasien stomatitis aftosa rekuren Correlation of TNF-α between lesional swab and peripheral blood of mononuclear cell of recurrent aphthous stomatitis patient," Dentofasial: Vol. 10: Iss. 2, Article 14.
DOI: 10.15562/jdmfs.v10i2.257
Available at: https://scholarhub.unhas.ac.id/dentofasial/vol10/iss2/14

Pages

71-75

Rights

©2016Ali Yusran, Erni Marlina, Sumintarti Sumintarti

DOI

10.15562/jdmfs.v10i2.257