Peranan matriks metaloproteinases pada lesi karies dentin Matrix metalloproteinase in caries dentine lesion

Authors

Fajriani Fajriani, Bagian Ilmu Kedokteran Gigi Anak Fakultas Kedokteran Gigi, Universitas Hasanuddin Makassar, IndonesiaFollow

Abstract

Matrix metalloproteinase (MMP) is a component extracelluler of matrix hydrolised which has an important role in
the process of biology and pathology. MMP has also a role in deficiency of dentine organic matrix due to
demineralization by bacterial acid and tooth caries development or controlling. MMP in host originates from saliva
and dentin. Saliva penetrate on the open dentinal lesion, and MMP in saliva had direct access to dentine
demineralization. It has been said that MMP saliva derived have a role in organic matrix destruction. Dentinal
matrix degradation is supposed acted by bacteria enzyme. It was clear that the cause of dentinal matrix degradation
is MMP-2 and MMP-9 in gelatinolitic process, and MMP-8 in collagenitic process. This paper was aimed to explain
about enzyme that has an important role in dentine caries.

Recommended Citation

Fajriani, Fajriani (2012) "Peranan matriks metaloproteinases pada lesi karies dentin Matrix metalloproteinase in caries dentine lesion," Dentofasial: Vol. 11: Iss. 1, Article 5.
DOI: 10.15562/jdmfs.v11i1.293
Available at: https://scholarhub.unhas.ac.id/dentofasial/vol11/iss1/5

Pages

45-48

Rights

©2016Fajriani Fajriani

DOI

10.15562/jdmfs.v11i1.293