Hubungan kualitas darah dengan konsentrasi transforming growth factor-β pada platelet rich plasma yang digunakan untuk regenerasi tulang dan jaringan periodontal (Correlation of blood quality with concentration of transforming growth factor-ß1 in platelet rich plasma for bone and periodontal tissue regeneration)

Authors

Surijana Mappangara, Bagian Bedah Mulut Fakultas Kedokteran Gigi Universitas Hasanuddin Makassar, IndonesiaFollow
Burhanuddin DP, Bagian Ilmu Kesehatan Gigi Masyarakat Fakultas Kedokteran Gigi Universitas Hasanuddin Makassar, IndonesiaFollow
Arni Irawaty Djais, Bagian Periodontologi Fakultas Kedokteran Gigi Universitas Hasanuddin Makassar, IndonesiaFollow

Abstract

This study aimed to explore the correlation of blood quality with transforming growth factor (TGF-ß1) of platelet rich
plasma (PRP) which was used for bone and periodontal tissue regeneration. Thirty nine subjects participated in this
study. Data of age, gender, eritrocyt, leucocyt, hemoglobin, thrombocyt, and TGF-ß1 concentration were used to
analyze the correlation using Spearman correlation test. This study found leucocyt, eritrocyt, hemoglobin, thrombocyt
concentration mean was 8.19 g/dl, 5.31 g/dl, 14.48 g/dl, 326.32 g/dl, respectively. The TGF-ß1 concentration mean
acquired from PRP was 31994.27 pg/ml. Based on Spearman correlation test, significant correlation was only
observed in eritrocyt concentration variable with p value 0.023 (p<0.05) and it was higher in male than in female. It
was concluded that TGF-ß1 concentration in PRP from normal subject was 31994.27 pg/ml. Based on leucocyt,
eritrocyt, hemoglobin, and thrombocyt test to TGF-ß1, only eritrocyt showed the significant relationship. This finding
also showed the linear correlation between the amoung of eritrocyt in blood with TGF-ß1 as the increased eritrocyt
value was followed by the excalated TGF-ß1 value.

Recommended Citation

Mappangara, Surijana; DP, Burhanuddin; and Djais, Arni Irawaty (2014) "Hubungan kualitas darah dengan konsentrasi transforming growth factor-β pada platelet rich plasma yang digunakan untuk regenerasi tulang dan jaringan periodontal (Correlation of blood quality with concentration of transforming growth factor-ß1 in platelet rich plasma for bone and periodontal tissue regeneration)," Dentofasial: Vol. 13: Iss. 2, Article 10.
DOI: 10.15562/jdmfs.v13i2.393
Available at: https://scholarhub.unhas.ac.id/dentofasial/vol13/iss2/10

Pages

80-85

Rights

©2016Surijana Mappangara, Burhanuddin DP, Arni Irawaty Djais

DOI

10.15562/jdmfs.v13i2.393