Abstract
Haruan is river-water fish usually consumed by South Kalimantan people. Haruan extract contains albumin, Zn, Fe,
Cu and unsaturated fatty acid which can act as antiinflammatory substances and accelarate wound healing. The aim of
this study is to examine effectiveness of haruan extract on lymphocyte count in infammatory phase of wound healing
process and compare it to ibuprofen. This study used true experimental method with post-test only control group design
and simple random sampling. Samples were divided into 5 treatment groups:which were given the extract for 7 seven
days: 25% haruan extract group, 50% haruan extract group, 100% haruan extract group, negative control K(-) using
aquadest, positive control K(+) given ibuprofen suspension with dosage of 20mg/kg weight/day. Lymphocyte cells were
observed using microscope and counted per field of view. Lymphocyte count reached its peak on day 5. Lymphocyte
count means in each group were 4,2 ± 0,566; 1± 0,000; 3,8 ± 2,546; 7,1 ± 0,141; dan 7,5 ± 3,818 respectively. Two
way ANOVA and post hoc LSD tests showed that lymphocyte count significantly decreased in 50% and 100% treatment
groups (p<0,05) and has equal effect with ibuprofen in decreasing lymphocyte count. This study concluded that haruan
extract significantly decreased lymphocyte count in wound healing process.
Recommended Citation
Izzaty, Arisa; Dewi, Nurdiana; and Pratiwi, Dewi Indah Noviana
(2014)
"Ekstrakharuan(Channa striata)secara efektif menurunkan jumlah limfosit fase inflamasi dalam penyembuhan luka (Extract of haruan (Channa striata) decreases lymphocyte count in inflammatory phase of wound healing process effectively),"
Dentofasial: Vol. 13:
Iss.
3, Article 5.
DOI: 10.15562/jdmfs.v13i3.411
Available at:
https://scholarhub.unhas.ac.id/dentofasial/vol13/iss3/5
Pages
176-181
Rights
©2016Arisa Izzaty, Nurdiana Dewi, Dewi Indah Noviana Pratiwi
DOI
10.15562/jdmfs.v13i3.411