Abstract
Introduction: Rhabdomyosarcoma (RMS) is the most common pediatric soft tissue sarcoma, often affecting the head and neck. This report presents a rare case of embryonal RMS in the buccal region, emphasizing diagnostic and therapeutic challenges.
Case Report: A 5-year-old boy presented with swelling in the left buccal region. Clinical examination revealed a firm mass. CT scan showed a heterogeneous lesion with necrosis, extending into adjacent spaces. Histopathology revealed spindle-shaped pleomorphic cells, and immunohistochemistry was positive for Desmin and Vimentin. The patient received six cycles of vincristine, adriamycin, and cyclophosphamide (VAC regimen), followed by radiotherapy. The tumor regressed completely with no residual disease on follow-up imaging.
Discussion: Accurate diagnosis required histopathology and immunohistochemistry. The case highlights the effectiveness of multimodal therapy, consistent with prior reports, though limited imaging restricted evaluation of minimal residual disease.
Conclusion: Early diagnosis and multidisciplinary treatment of pediatric buccal RMS are critical for favorable oncologic and functional outcomes.
Keywords: Buccal mass, Child, Embryonal rhabdomyosarcoma, Immunohistochemistry
Recommended Citation
Ridha, Nadirah R.; Kasriyanti, Wa O.; Sulmiati; and Purnama, Imeldy P.
(2025)
"Embryonal rhabdomyosarcoma of the buccal region in a pediatric patient: A case report and review of the literature,"
Journal of Dentomaxillofacial Science: Vol. 10:
Iss.
4, Article 6.
DOI: https://doi.org/10.15562/jdmfs.v10i4.2088
Available at:
https://scholarhub.unhas.ac.id/jdmfs/vol10/iss4/6
Pages
224-227
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Rights
©2025Nadirah R. Ridha, Wa O. Kasriyanti, Sulmiati, Imeldy P. Purnama
DOI
10.15562/jdmfs.v10i4.2088