Abstract
Objective: The aim of this study is to examine cytotoxicity differences between ethanol extract of A. muricata roots and leaves against HSC-3 cell line.
Material and Methods: HSC-3 cell lines were treated with ethanol extracts of A. muricata roots and leaves with 100, 30, 10, and 1 μg/mL concentrations for 24 hours. The percentage of cell viability was measured using MTT assay.
Results: The results showed significant differences (p <0.001) of treatments group compared to negative control. Ethanol extract of A. muricata roots showed the highest cytotoxicity against HSC-3 cell lines.
Conclusion: There is difference in cytotoxicity between ethanol extracts of A. muricata roots and leaves against HSC-3 cell lines where root extracts showed higher cytotoxicity.
Recommended Citation
Rizki, Naftalia M. and Roeslan, Moehamad O.
(2023)
"Cytotoxicity differences from roots and leaves ethanol extracts of Annona muricata Linn on HSC-3,"
Journal of Dentomaxillofacial Science: Vol. 8:
Iss.
2, Article 2.
DOI: https://doi.org/10.15562/jdmfs.v8i2.1593
Available at:
https://scholarhub.unhas.ac.id/jdmfs/vol8/iss2/2
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
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©2023Naftalia M. Rizki, Moehamad O. Roeslan
DOI
10.15562/jdmfs.v8i2.1593